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Publications

2009

Applegate RW Jr, Marr DW, Squier J, Graves SW (2009) Particle size limits when using optical trapping and deflection of particlesfor sorting using diode laser bars, Opt Express. Sep 14;17(19):16731-8.

Carr C, Espy M, Nath P, Martin SL, Ward MD, Martin J (2009) A magnetophoresis chamber with 25 fractions output – design, fabrication and demonstration, Journal of Magnetism and Magnetic Materials 321: 1440-1445.

Chen J, Zhou J, Sanders CK, Nolan JP, Cai H. (2009) A surface display yeast two-hybrid screening system for high-throughput protein interactome mapping, Anal Biochem. Jul 1;390(1):29-37. Epub 2009 Mar 17.

Gabbard J, Velappan N, Di Niro R, Schmidt J, Jones CA, Tompkins SM, Bradbury ARM (2009) A humanized anti-M2 scFv shows protective in vitro activity against influenza, Protein Engineering, Design & Selection 22(3) 189–198.

Jett JH, Martin JC, Habbersett RC (2009) Techniques for flow cytometer alignment, Curr Protoc Cytom. Oct;Chapter 1:Unit 1.10.

Lauer S, Kunde YA, Apodaca TA, Goldstein B, Hong-Geller E (2009) Soluble MD2 increases TLR4 levels on the epithelial cell surface, Cellular Immunology 255(1-2): 8-16.

Marrone BL. Flow Cytometry: A Multipurpose Technology for a Wide Spectrum of Global Biosecurity Applications, Journal of the Association for Laboratory Automation 14(3): 148-156, June 2009.

Naivar MA, Wilder ME, Habbersett RC, Woods TA, Sebba DS, Nolan JP, Graves SW
(2009) Development of small and inexpensive digital data acquisition systems using a microcontroller-based approach, Cytometry 75A:979-989.


Saunders MJ, Graves SW, Sklar LA, Oprea TI, Edwards BS (2009)High-Throughput Multiplex Flow Cytometry Screening for Botulinum Neurotoxin Type A Light Chain Protease Inhibitors, Assay Drug Dev Technol Dec 28.

Watson DA, Gaskill DF, Brown LO, Doorn SK, Nolan JP (2009) Spectral measurements of large particles by flow cytometry, Cytometry A 75 5 May pp.460-4.

 

2008

 

Chen J, Zhou J, Bae W, Sanders CK, Nolan JP, Cai H (2008) A yEGFP-Based Reporter System for High-Throughput Yeast Two-Hybrid Assay by Flow Cytometry.  Cytometry Part A, 73A:312-320.

 

Goddard GR, Houston JP, Martin JC, Graves SW, Freyer JP (2008) Cellular Discrimination Based on Spectral Analysis of Instrinic Flourescence. Proc. SPIE, 6859:685908.

 

Houston JP, Naivar M, Martin JC, Goddard G, Carpenter S, Mourant JR, Freyer JP (2008) Endogenous Fluorescence Lifetime of Viable Cells by Flow Cytometry. Proc. SPIE, 6859: 68590T.

 

Jett JH (2008) Raman Spectroscopy Comes to Flow Cytometry. Cytometry Part A, 73A:109-110.

 

Watson DA, Brown LO, Gaskill DF, Naivar M, Graves SW, Doorn SK, Nolan JP (2008) A flow Cytometer for the Measurement of Raman Spectra. Cytometry Part A, 73A:119-128.

 

2007


Ayriss J, Woods T, Bradbury A, Pavlik P (2007) High-throughput screening of single-chain antibodies using multiplexed flow cytometry. J. Proteome Res., 6: 1072-82.


Goddard GR, Sanders CK, Martin JC, Kaduchak G, Graves SW (2007) Analytical performance of an ultrasonic particle focusing flow cytometer. Anal. Chem., 79: 8740-8746.


Habbersett RC, Naivar MA, Woods TA, Goddard GR, Graves SW (2007) Evaluation of a green laser pointer for flow cytometry. Cytometry, 71A (10): 809-917.

Naivar MA, Parson JD, Wilder ME, Habbersett RC, Edwards BS, Sklar L, Nolan JP, Graves SW, Martin JC, Jett JH, Freyer JP (2007) Open, reconfigurable cytometric acquisition system: ORCAS. Cytometry, 71A (11): 915-924.

Ramachandrian J, Powers TM, Carpenter S, Garcia-Lopez A, Freyer JP, Mourant JR (2007) Light scattering and microarchitectural differences between tumorigenic and non-tumorigenic cell models of tissue. Optics Express, 15: 4039-4053..

Sandin H, Carr C, Matlachov AN, Hanson CJ, Martin JC, Ward MD, Kraus RH, Espy MA (2007) Magnetophoresis and cytometry with magnetic microparticles. Int. Congr. Ser, in press.

Zhong W, Shou Y, Yoshida TM, Marrone BL (2007) Differentiation of Bacillus anthracis, B. cereus, and B. thuringiensis by using pulsed field gel electrophoresis. Appl. Environ. Microbiol., 73: 3446-2449.

2006


Despande A, Hammon RJ, Sanders CK, Graves SW (2006) Quantitative analysis of the effect of cell type and cellular differentiation on protective antigen binding to human target cells. FEBS Lett. 580: 4172-4175.

Du Y, Gu S, Zhou J, Wang T, Cai H, MacInnes M, Bradbury EM, Chen X (2006) The dynamic alterations of H2AX complex during DNA repair detected by a proteomic approach reveal the critical roles of Ca2+/calmodulin in the ionizing radiation induced cell cycle arrest. Molec. Cell. Proteomics 5: 1033-1044.

Espy MA, Sandin H, Carr C, Hanson CJ, Ward MD, Kraus RH (2006) An instrument for sorting of magnetic microparticles in a magnetic field gradient. Cytometry 69A: 1132-1142.

Goddard G, Martin JC, Graves SW, Kaduchak G (2006) Ultrasonic particle-concentration for sheathless focusing of particles for analysis in a flow cytometer. Cytometry 69A: 66-74.

Goddard G, Martin JC, Naivar M, Goodwin PM, Graves SW, Habbersett RC, Nolan JP, Jett JH (2006) Single particle high resolution spectral analysis flow cytometry. Cytometry A 69: 842-851.

Kiss C, Fisher H, Pesavento E, Dai M, Valero R, Ovecka M, Nolan R, Phipps ML, Velappan N, Chasteen L, Martinez JS, Waldo GS, Pavlik P, Bradbury ARM (2006) Antibody binding loop insertions as diversity elements. Nucl. Acids Res. 34: e132.

Mourant JR, Dominguez J, Carpenter S, Short KW, Powers TM, Michalczyk R, Kunapareddy N, Trujillo A, Guerra A, Freyer JP (2006) Comparison of vibrational spectroscopy to biochemical and flow cytometry methods for analysis of the basic biochemical composition of mammalian cells. J. Biomed. Optics 11 (6): 064024.

Pedelacq JD, Cabantous S, Tran T, Terwilliger TC, Waldo GS (2006) Engineering and characterization of a superfolder green fluorescent protein. Nat. Biotech. 24: 79-88.

Saunders MJ, Kim H, Woods TA, Nolan JP, Sklar LA, Edwards BE, Graves SW (2006) Microsphere based protease assays and screening application for lethal factor and factor Xa. Cytometry A 69: 342-352.

Wang TY, Chuang TH, Ronni T, Gu S, Du YC, Cai H, Sun HQ, Yin HL, Chen X (2006) Flightless 1 homology negatively modulates the TLR pathway. J. Immunol. 3: 1355-1362.



2005


Cram LS and Arndt-Jovin D (2005) Mack Jett Fulwyler: Pioneer of Flow Cytometry and Flow Sorting (1936-2001). Cytometry 67A: 53-54.

Deshpande A, Nolan JP, White PS, Valdez YE, Hunt WC, Peyton CL, Wheeler CM (2005) TNF Alpha-Promoter Polymorphisms and Susceptibility to HPV16-Associated Cervical Cancer. Journal of Infectious Diseases 191: 969-976.

Deshpande A, Valdez YE, Nolan JP (2005) Multiplexed SNP genotyping using single base primer extension (SBE) and microsphere arrays. In: Current Protocols in Cytometry, Robinson JP, Darzynkiewicz Z, Dobrucki J, Hyun WC, Nolan JP, Orfao A, Rabinovitch PS, ed. (Wiley Interscience, New York) Chapter 13.4: 13.4.1-13.4.11.

Ferris MM, Yoshida TM, Marrone BL, Keller RA (2005) Fingerprinting of single viral genomes. Analytical Biochemistry 337: 278-288.

Goddard G, Kaduchak G (2005) Ultrasonic particle concentration in a line-driven cylindrical tube. J. Acoust. Soc. Am. 117: 3440-3447.

Graves SW, Nolan JP, Sklar LA (2005) Molecular assemblies, probes and proteomics in flow cytometry. In: Flow Cytometry in Biotechnology, Sklar LA, ed. (Oxford University Press, London) Chapter 9: 153-177.

Graves SW, Woods TA, Kim H, Nolan JP (2005) Direct fluorescent staining and analysis of proteins on microspheres using CBQCA. Cytometry A 65: 50-58.


Jiang Y, Pjesivac-Grbovic J, Cantrell C, Freyer JP (2005) A multiscale model for avascular tumor growth. Biophys. J. 89: 3884-3894.

Marrone BL, Habbersett RC, Jett JH, Keller RA, Yan X, Yoshida TM (2005) DNA fragment sizing by high-sensitivity flow cytometry: applications in bacterial identification. In: Flow Cytometry in Biotechnology, Sklar LA, ed. (Oxford University Press, London) Chapter 7: 123-138.

Mourant J, Kunapareddy P, Carpenter S, Freyer JP (2005) Vibrational spectroscopy for identification of biochemical changes accompanying carcinogenesis and the formation of necrosis. Gynecol. Oncol. 99: S58-S60.

Mourant JR, Short KW, Carpenter S, Kunapareddy N, Coburn L, Powers TM, Freyer JP (2005) Biochemical differences in tumorigenic and nontumorigenic cells measured by Raman and infrared spectroscopy. J. Biomed. Opt. 10: 1-15.

Nolan JP, Despande A, Zhou F (2005) Genetic analysis using microsphere arrays. In: Flow Cytometry in Biotechnology, Sklar LA, ed. (Oxford University Press, London) Chapter 14: 259-274.

Short KW, Carpenter S, Freyer JP, Mourant JR (2005) Raman spectroscopy detects biochemical changes due to proliferation in mammalian cell cultures. Biophys. J. 88: 4272-4288.

Werner JH, Cai H, Keller RA, Goodwin PM (2005) Exonuclease I hydrolyzes DNA with a distribution of rates. Biophysical J. 88,2: 1403-12.

Woods TA, Graves SW, Nolan JP (2005) Microsphere surface protein determination using flow cytometry. In: Current Protocols in Cytometry, Robinson JP, Darzynkiewicz Z, Dobrucki J, Hyun WC, Nolan JP, Orfao A, Rabinovitch PS, ed. (Wiley Interscience, New York) Chapter 13.2: 13.2.1-13.2.13.

Yan X, Habbersett RC, Yoshida TM, Nolan JP, Jett JH, Marrone BL (2005) Probing the kinetics of SYTOX Orange stain binding to double-stranded DNA with implications for DNA analysis. Anal. Chem. 77: 3554-3562.

Yan X, Zhong W, Tang A, Schielke EG, HHang W, Nolan JP (2005) Multiplexed flow cytometric immunoassay for influenza virus detection and differentiation. Anal. Chem. 77: 7673-7678.



2004


Cleland, C., P.S. White, A. Deshpande, M. Wolinsky, J. Song, and J.P. Nolan. Development of Rationally Designed Nucleic Acid Signatures for Microbial Pathogens. Expert Review of Molecular Diagnostics 4(3):303-315, 2004 .

Cram, L.S., J.W. Gray, and N.P. Carter, Cytometry and Genetics. Cytometry 58,33-36, 2004.

Ferris, M..M., X.M. Yan, R.C. Habbersett, Y.L. Shou, C.L. Lemanski, J.H. Jett, T.M. Yoshida, and B.L. Marrone. Performance assessment of DNA fragment sizing by high sensitivity flow cytometry and pulsed field gel electrophoresis, J. Clin. Microbiol. 42, 1965-1976, 2004.

Ferris, M. M., R.C. Habbersett, M. Wolinsky, J.H. Jett, T.M. Yoshida, and R.A. Keller. Statistics of Single-Molecule Measurements: Applications in Flow-Cytometry Sizing of DNA Fragments. Cytometry Part A 60A:41-52, 2004.

Goodwin, P.M., R.L. Nolan, and H. Cai. Single-Molecule Spectroscopy for Nucleic Acid Analysis: A New Approach for Disease Detection and Genomic Analysis. Curr. Pharm. Biotechno 5, 3:271-8, 2004.

Habbersett, R.C. and J.H. Jett. An analytical system based on a compact flow cytometer for DNA fragment sizing and single-molecule detection. Cytometry Part A 60A: 125-134, 2004.


Jett, J.H.; Molecular Cytometry; Journal of Biological Regulators and Homeostatic Agents 18:352-356, 2004.

Pannucci, J.*, H. Cai*, P. Pardington, E. Williams, R.T. Okinaka, C.R. Kuske, and R.B. Cary. Virulence Signatures: Microarray-based Approaches to Discovery and Analysis. J. Biosensors & Bioelectronic 2004 20, 4: 706-18, 2004. * equal contributor as the first author

Yan, X.M., E.G. Schielke, K.M. Grace, C. Hassell, B.L. Marrone, J.P. Nolan, Microsphere-based duplexed immunoassay for influenza virus typing by flow cytometry. J. Immunol. Methods, 284, 27-38, 2004.

Yan, X.M., A.J. Tang, E.G. Schielke, W. Hang, J.P. Nolan. On the development of a microsphere-based multiplexed immunoassay for influenza virus typing and subtyping by flow cytometry. International Congress Series 1263, 342-345, 2004.



2003


Ambrose, W.P., H. Cai, P.M. Goodwin, J.H. Jett, R.C. Habbersett, E.J. Larson, W.K. Grace, J.H. Werner, and R.A. Keller (2003) Flow Cytometric Sizing of DNA Fragments for Topics in Fluorescence Spectroscopy, Vol. 7, DNA Technology, Plenum Press, J. R. Lakowicz, Ed.
Budowle, B; Schutzer, SE; Einseln, A; Kelley, LC; Walsh, AC; Smith, JAL; Marrone, BL; Robertson, J; Campos, J (2003)  Building microbial forensics as a response to bioterrorism. Science 301, 1852-1853

Cui, HH; Valdez, JG; Steinkamp, JA; Crissman, HA (2003) Fluorescence lifetime-based discrimination and quantification of cellular DNA and RNA with phase-sensitive flow cytometry. Cytometry Part A 52A, 46-55.

Graves, S.W., J.P. Nolan, L.A. Sklar (2003) Molecular assembly analysis using flow cytometry. In Flow Biotechnology (LA Sklar, ed) Academic Press, New York (in press).

Kaderali, L, A. Deshpande, JP Nolan, PS White (2003) Primer design for multiplexed genotyping. Nucleic Acids Research 31:1796-1802.

Mourant, JR; Yamada, YR; Carpenter, S; Dominique, LR; Freyer, JP (2003) FTIR spectroscopy demonstrates biochemical differences in mammalian cell cultures at different growth stages. Biophysical Journal 85, 1938-1947.

Nolan J.P., A. Deshpande, F. Zhou (2003) Genetic Analysis Using Microsphere Arrays. In Flow Biotechnology (LA Sklar, ed) Academic Press, New York (in press).

Nolan, R.L., H. Cai, J.P. Nolan, J.P., PM Goodwin (2003) A simple quenching method for fluorescence background reduction and its application to the direct, quantitative detection of specific mRNA. Analytical Chemistry 75: 6236-43.

Werner, JH; Cai, H; Jett, JH; Reha-Krantz, L; Keller, RA; Goodwin, PM (2003) Progress towards single-molecule DNA sequencing: a one color demonstration. Journal of Biotechnology 102, 1-14.


Yan, X., E.G. Schielke, K.M. Grace, C. Hassell, B.L. Marrone, and J.P. Nolan (2003) Microsphere-based duplexed immunoassay for influenza virus typing by flow cytometry. J. Immunological Methods 284, 27-38.



2002


Cram LS, CS Bell, and JJ Fawcett (2002) Chromosome sorting and genomics. Methods in Cell Science 24:27-35

Cram, L.S. (2002) Flow Cytometry, An Overview. Methods in Cell Science 24, 1-9.

Cui, H.H., J.G. Valdez, J.A. Steinkamp, and H.A. Crissman. (2001) Fluorescence Lifetime Discrimination of Cellular DNA and RNA with Various Intercalating Dyes and Flow Cytometric Analysis. In: Proceedings of the BiOS 2001 SPIE Meeting, San Jose, California, 20-26 January 2001.

Goodwin, P.M., H. Cai, W.K. Grace, E.J. Larson, B.L. Marrone, J.H. Jett, J.H. Werner, and R.A. Keller (2002) Single Molecule Nucleic Acid Analysis by Fluorescence Flow Cytometry, Integrated Technologies for Drug Discovery, 2000.

Goodwin, P.M., H. Cai, W.K. Grace, E.J. Larson, J.H. Jett, J.H. Werner, and R.A. Keller (2002) Single Molecule Nucleic Acid Analysis by Fluorescence Flow Cytometry, NATO Advanced Workshop Series, Polymer Structure and Transport in Confined Spaces.

Graves, S.W., J.P. Nolan, J.H. Jett, J.C. Martin, L.A. Sklar (2002) Effects of nozzle design on rapid delivery in flow cytometry. Cytometry 43:23-30.

Graves, S.W., R.C. Habbersett, J.P. Nolan (2002) Dynamic temperature control of the sample in flow cytometry. Current Protocols in Cytometry (in press).

Jett, J.H., H. Cai, B. Edwards, R.C. Habbersett, E.J. Larson, B.L. Marrone, J.P. Nolan, L.A. Sklar, X. Song, B. Swanson, P.S. White, and R.A. Keller. Flow Cytometry Analysis Techniques for High Throughput Biodefense Research. Automation in Threat Reduction and Infectious Disease Research: Needs and New Directions, National Academy of Sciences. April 1999, Washington, D.C.

Lauer, S., B. Goldstein, R. Nolan, J.P. Nolan (2002) Analysis of cholera toxin-ganglioside interactions by flow cytometry. Biochemistry 41:1742-1751.

Lauer, S., J.P. Nolan (2002) Development and characterization of Ni-NTA microspheres. Cytometry 48:136-145.

Nolan J.P., Mandy F.F. (2002) Suspension array technology: New tools for gene and protein analysis. Cellular and Molecular Biology 47:1241-1256.

Nolan J.P., White PS (2002) Biosensor platforms and assays.  Proceedings of BTR 2002: Unified Science & Technology for Reducing Biological Threats & Countering Terrorism.

Nolan, J.P., LA Sklar (2002) Suspension array technology: evolution of the flat array paradigm. Trends in Biotechnology 20:9-12.

Nolan, J.P., P.S. White, H. Cai (2002) SNP scoring for drug discovery applications. In, Integrated Drug Discovery Technologies (H.-Y. Mei and A. Czarnik, eds), pp 149-166, Marcel Dekker, New York.

Sklar, LA, B Edwards, SW Graves, JP Nolan, E Prossnitz (2002) Flow cytometric analysis of ligand-receptor interactions and molecular assemblies. Annual Review of Biophysics and Biomolecular Structure 31: 97-119.



2001


Cram, L.S. (2001) Spin-Offs From the NASA Space Program for Tumor Diagnosis., Cytometry 43, 1.

Crissman, H.A. and J.A. Steinkamp. Flow Cytometric Fluorescence Lifetime Measurements. In Methods in Cell Biology: Cytometry, Third Edition, Volume 63, Editors: Z. Darzynkiewicz, H.A. Crissman and J.P. Robinson (eds.) Academic Press, NY, pp 131-148 (2001).

Edwards B., F. Kuckuck, E. Prossnitz, A. Okun, J. Ransom, and L.A. Sklar. Plug Flow Cytometry Extends Analytical Capabilities in Cell Adhesion and Receptor Pharmacology. Cytometry 43:211-216 (2001).

Edwards B., F. Kuckuck, E. Prossnitz, J. Ransom, and L.A. Sklar. HTPS Flow Cytometry. Biomolecular Screening 6:83-90 (2001).

Emory, S.R., W.P. Ambrose, P.M. Goodwin, and R.A. Keller. Observing Single Molecule Chemical Reactions on Metal Nanoparticles. Proceedings of SPIE - The International Society for Optical Engineering; v.4258, p.63-72 (2001).

Graves, S.W., R.C. Habbersett, and J.P. Nolan. A Dynamic Inline Sample Thermoregulation Unit for Flow Cytometry. Cytometry 43:23-30 (2001).

Kuckuck, F., B. Edwards, and L.A. Sklar. High Throughput Flow Cytometry. Cytometry 44:83-90 (2001).

Lehnert, N.M., R.K. Gary, B.L. Marrone, and B.E. Lehnert. Inhibition of Normal Human Lung Fibroblast Growth by Beryllium. Toxicology 160:119-127 (2001).

Steinkamp, J.A. and J.D. Parson. (2001) Flow Cytometric, Time-Resolved Measurements by Frequency Heterodyning of Fluorescence Emission Signals. BiOS 2001 SPIE International Symposium on Advanced Techniques in Analytical Cytology.

Steinkamp, J.A., Y.E. Valdez, and B.E. Lehnert. (2001) Flow Cytometric, Phase-Resolved Discrimination of Damaged/Dead Cells by Propidium Iodide Uptake in Macrophages Having Phagocytized Fluorescent Microspheres. BiOS 2001 SPIE International Symposium on Advances in Fluorescence Sensing Technology V.

White, P.S., P. Kwok, P. Oefner, and A.J. Brookes. (2001) Polymorphsim and Complex Genome Analysis: SNPs: Some Notable Progress. European Journal of Human Genetics.



2000


Bennett, T, B.E. Edwards, L.A. Sklar, and S. Rogelj. Sulfhydryl Regulation of L-Selectin Shedding in Neutrophils. Phenylarsine Oxide Promotes Activation Independent L-Selectin Shedding from Neutrophils. J. Immunol. 164:4120-4129 (2000).

Burchiel, S.W., B.S. Edwards, F.W. Kuckuck, F.T. Lauer, E.R. Prossnitz, and L.A. Sklar. Analysis of Free Intracellular Calcium by Flow Cytometry: Examples of Multiparameter and Pharmacological Applications. Methods: A Companion to Methods in Enzymology, 21:221-230 (2000).

Cai, H., P.S. White, D.C. Torney, A. Deshpande, Z. Wang, R.A. Keller, B. Marrone, and J.P. Nolan. Flow Cytometry Based Minisequencing: A New Platform for High Throughput Single Nucleotide Polymorphism Analysis. Genomics 66:135-143 (2000).

Edwards, B.S., M.S. Curry, H. Tsuji, D. Brown, R.S. Larson, and L.A. Sklar. Expression of P-selectin at Low Site Density Promotes Selective Attachment of Eosionphils over Neutrophils. J. Immunol. 165:404-410 (2000).

Farris, G.M., L.S. Newman, E.L. Frome, Y. Shou, E. Baker, R.C. Habbersett, L. Maier, H.N. Smith, and B.L. Marrone. Detection of Beryllium Sensitivity using a Flow Cytometric Lymphocyte Proliferation Test: The Immuno-Be-LPT. Toxicology 143:125-140 (2000).

Farris, G.M., Y. Shou, R.C. Habbersett, N. Lehnert, B. Lehnert, L.S. Newman, and B.L. Marrone. Hypersensitivity to Beryllium Detected by Lymphosyte Subset Proliferation Testing: The Immuno-LPT. Toxicology 143:125-140 (2000).

Habbersett, R.C., J.H. Jett, and R.A. Keller. Single DNA Fragment Detection by Flow Cytometry, in: Emerging Tools for Cell Analysis: Advances in Optical Measurement Technologies, G. Durack and J. P. Robinson, Eds., Wiley-Liss: New York, Pgs 115-138 (2000).

Iyer, R. B.E. Lehnert and R. Svernsson. Factors Underlying the Cell Growth-Related Bystander Responses to alpha Particles. Cancer Research 60:1290 (2000).

Keij, J.F., C. Bell-Prince, and J. A. Steinkamp. Staining of Mitochondrial Membranes With 10-Nonyl Acridine Orange, MitoFluor Green and MitoTracker Green is Affected by Mitochondrial Membrane Potential Altering Drugs. Cytometry 39:203-210 (2000).

Larson, E.J., J.R. Penttila, H. Cai. J.H. Jett, S. Burde, R.A. Keller, and B.L. Marrone. Rapid DNA Fingerprinting of Pathogens by Flow Cytometry. Cytometry 41:302-308 (2000).

Lehnert, B.L. and R. Iyer. Cell Growth-Related Bystander Responses to a Particles and g Rays. Proceedings of Radiation Research 8:488 (2000).

Ransom, J.T., B.S. Edwards, F.W. Kuckuck, A. Okun, D.K. Mattox, E.R. Prossnitz and L.A. Sklar. Flow Cytometry Systems for Drug Discovery and Development. Proceedings of SPIE, 3921:90-100 (2000).

Sklar, L.A. Funding for Core Facilities: A ManagerÆs Manifesto In Living Color--Protocols in Flow Cytometry and Cell Sorting, edited by Diamond and DeMaggio, Landes and Co., pp. 642-654 (2000).

Sklar, L.A., J. Vilven, E. Lynam, D. Neldon, T. Bennett, and E.R. Prossnitz. Solubilization and Display of 7TMR on Beads for Real-Time Fluorescence and Flow Cytometric Analysis. Biotechniques 28:976-985 (2000).

Steinkamp, J.A. Fluorescence Lifetime Flow Cytometry. In: Emerging Tools for Cell Analysis: Advances in Optical Measurement (G. Durack and J. P. Robinson, eds.), John Wiley and Sons, New York, NY, pp. 175-192 (2000).

Steinkamp, J.A. Time-Resolved Fluorescence Measurements. In: Current Protocols in Cytometry (J. P. Robinson, managing ed.), John Wiley and Sons, NY, Suppl. 11, pp. 1.15.1-1.15.16 (2000).

Steinkamp, J.A., Y.E. Valdez, and B.E. Lehnert. Flow Cytometric, Phase-Resolved Fluorescence Measurement of Propidium Iodide Uptake in Macrophages Containing Phagocytized Fluorescent Microspheres. Cytometry 39:45-55( 2000).

Van Orden, A., W.P. Ambrose, and R.A. Keller. High Throughput DNA Fragment Length Analysis. Anal. Chem. 72:37 (2000).

Werner, J.H., E.J. Larson, P.M. Goodwin, W.P. Ambrose, and R.A. Keller. Effects of Fluorescence Excitation Geometry on the Accuracy of DNA Fragment Sizing by Flow Cytometry. Appl. Opt., 39:2831 (2000).

Yan, X, R.C. Habbersett, J.M. Cordek, J.P. Nolan, T.M. Yoshida, J.H. Jett, and B.L. Marrone. Development of a Mechanism-Based, DNA Staining Protocol Using SYTOX Orange Nucleic Acid Stain and DNA Fragment Sizing Flow Cytometry. Analytical Biochemistry 286:138 ù148 (2000).



1999


Ambrose, W.P., P.M. Goodwin, J.H. Jett, A. Van Orden, J.H. Werner, and R.A. Keller. Single Molecule Fluorescence Spectroscopy at Ambient Temperature. Chem. Rev. 99:2929 (1999).


Ambrose, W.P., P.M. Goodwin, and J.P. Nolan. Single Molecule Detection with Total Internal Reflection Excitation: Comparing Signal to Background and Total Signal in Different Geometries. Cytometry 36:224-231 (1999).


Buranda, T., G. Jones, J.P. Nolan, J. Keij, G.P. Lopez, and L.A. Sklar. Ligand-Receptor Dynamics at Streptavidin-Coated Particle Surfaces: A Flow Cytometric and Spectrofluorometric Study. J. Phys. Chem. 103:3399 (1999).

Buranda, T., G.P. Lopez, J. Keij, R. Harris, and L.A. Sklar. Peptides, Antibodies, and FRET on Beads in Flow Cytometry: a Model System Using Fluoresceinated and Biotinylated beta-Endorphin. Cytometry 37:21 (1999).

Burma, S., A. Kurimasa, G. Xie, Y. Taya, R. Araki, M. Abe, H.A. Crissman, G.C. Li and D.J. Chen. DNA-Dependent Protein Kinase-Independent Activation of p53 in Response to DNA Damage. J Biol Chem. 274:17139-17143 (1999).

Edwards, B.E., F. Kuckuck, and L.A. Sklar. Plug-Flow Flow Cytometry: An Automated Coupling Device for Rapid Sequential Flow Cytometric Sample Analysis. Cytometry 37:156-159 (1999).

Gary, R., M.S. Park, J.P. Nolan, H.L. Cornelius, O.G. Korzyreva, H.P. Tran, K.S. Lobachev, M.A. Resnick, and D.A. Gordenin. A Novel Role in DNA Metabolism for Binding of Fen1/Rad27 to PCNA-and Implications for Genetic risk. Molecular and Cell Biology 19:5373-5382 (1999).

Gilbert. T., E.R. Prossnitz, and L.A. Sklar. The Uncoupled State of the Formyl Peptide Receptor. J. Sig. Trans. and Rec. Res. Jan. 19:327-3401(1999).

Huang, Z., J.H. Jett, and R.A. Keller. Bacteria Genome Fingerprinting by Flow Cytometry. Cytometry 35:169 (1999).

Jones, G., C. Wistrom, C. Wofsy, and L.A. Sklar. Analysis of Vertical Energy Transfer in Small Micelles. Biophys J. 76:517 (1999).

Keij, J.F., C. Bell-Prince, and J.A. Steinkamp. Simultaneous Analysis of Relative DNA and Glutathione Content in Viable Cells Using Phase-Resolved Flow Cytometry. Cytometry 35:48-54 (1999).

Kim, Y., J.H. Jett, E.J. Larson, J.R. Penttila, B.L. Marrone, and R.A. Keller. Bacterial Fingerprinting by Flow Cytometry: Bacterial Species Identification. Cytometry 36:324 (1999).

Prossnitz,E.R., T. Gilbert, S. Chiang, J.J. Campbell, S. Qin, W. Newman, L.A. Sklar, and R.D. Ye. Mutliple Activation Steps of the N-Formyl Peptide Receptors. Biochemistry 38:2240-2247 (1999).

Seamer, L.C., F. Kuckuck, and L.A. Sklar. Sheath Control to Permit Stable Flow in Rapid Mix Flow Cytometry. Cytometry 35:75 (1999).

Steinkamp, J.A. Phase-Sensitive Flow Cytometry: Fluorescence Lifetime-Based Sensing Technology For Analyzing Cells Labeled With Fluorescent Probes. Proceedings Lasers æ98 XXI International Conference on Lasers and Laser Applications. Society for Optical and Quantum Electronics, McLean, VA, pp. 633-640 (1999).

Steinkamp, J.A. Phase-Sensitive Flow Cytometry: Fluorescence Lifetime-Based Sensing Technology for Analyzing Free Fluorophore and Cells/Particles Labeled with Fluorescent Probes. Advanced Materials and Optical Systems for Chemical and Biological Detection, Proceedings of SPIE 3858:151-160 (1999).

Steinkamp, J.A. and J.F. Keij. Elimination of Light Scatter Interference in Dual-Laser Flow Cytometry by Synchronous Detection of Emitted Fluorescence: Theory and Demonstration Using Simulated Signals. Proceedings of Advanced Techniques in Analytical Cytology III, SPIE 3604:170-176 (1999).

Steinkamp, J.A. and J.F. Keij. Fluorescence Intensity and Lifetime Measurement of Free and Particle-Bound Fluorophore in a Sample Stream by Phase-Sensitive Flow Cytometry. Rev. Sci. Instrum. 70:4682-4688 (1999).

Steinkamp, J.A., N.M. Lehnert, J.F. Keij, and B.E. Lehnert. Enhanced Immunofluorescence Measurement Resolution of Surface Antigens on Highly Autofluorescent, Glutaraldehyde-Fixed Cells by Phase-Sensitive Flow Cytometry. Cytometry 37:275-283 (1999).

Steinkamp, J.A., B.E. Lehnert, and N.M. Lehnert. Discrimination of Damaged/dead Cells by Propidium Iodide Uptake in Immunofluorescently Labeled Populations Analyzed by Phase-Sensitive Flow Cytometry. J. Immunol. Meth. 226:59-70 (1999).

Steinkamp, J.A., B.E. Lehnert, and N.M. Lehnert. Flow Cytometric Lifetime-Based Cell Viability Assay Using Propidium Iodide. Proceedings of Advances in Fluorescence Sensing Technology IV, SPIE 3602:15-23 (1999).

Van Orden, A., H. Cai, P.M. Goodwin, and R.A. Keller. Efficient Detection of Single DNA Fragments in Flowing Sample Streams by Two-Photon Fluorescence Excitation. Anal. Chem. 71:2108 (1999).

Yan, X.M., W.K.Grace, T.M. Yoshida, R.C. Habbersett, N. Velapan, J.H. Jett, R.A. Keller, and B.L. Marrone, Characteristics of Different Nucleic Acid Staining Dyes for DNA Fragment Sizing by Flow Cytometry. Anal. Chem. 71:5470-5480 (1999).


Zenin, V.V., N.D. Aksenov, A.N. Shatrova, N.V. Kopov, L.S. Cram, and A.I. Poletaev. A Device for the Preliminary Treatment of Samples Upon Flow Cytometry Analysis. Biofizika 44:303-312 (1999).



1998


Ambrose, W.P., D.J. Semin, D.L. Robbins, A. Van Orden, M.A. Kashem, S.A. Hamilton, R.N. Nelson, J.H. Jett, and R.A. Keller. Detection System for Reaction-Rate Analysis in a Low-Volume Proteinase-Inhibition Assay. Anal. Biochem., 263:150 (1998).

Bergstrom, D.E., D.A. Grieco, M.M. Sonti, J.J. Fawcett, C. Bell-Prince, L.S., Cram, S. Narayanswami, and E.M. Simpson. The Mouse Y Chromosome: Enrichment, Sizing, and Cloning by Bivariate Flow Cytometry. Genomics 48:304-313 (1998).

Cai H., K. Kommander, P.S. White, R.A. Keller, and J.P. Nolan. Flow Cytometry-Based Hybridization and Polymorphism Detection and Analysis. In Advances in Optical Biophysics. (Eds. J.R. Lakowicz and J.B.A. Ross) Proceedings SPIE 3256:171-177 (1998).

Cobo, J.M., R. Garcia-Canero, J.G. Valdez, A.M. Barrasso, B.L. Sailer, and H.A. Crissman. Attenuation of Apoptotic DNA Fragmentation by Amiloride. J. Cell Physiol. 175:59-67 (1998).

Curtis, L.J., Y. Li, M. Gerbault-Seureau, R. Kuick, A-M. Dutrillaux, G. Goubin, J. Fawcett, S. Cram, B. Dutrillaux, S. Hanash, M. Muleris. Amplification of DNA Sequences from Chromosome 19q13.1 in Human Pancreatic Cell Lines. Genomics 53:42-55 (1998).

Demas, J.N., M. Wu, P.M. Goodwin, R.L. Affleck, and R.A. Keller. Fluorescence Detection in Hydrodynamically Focused Streams: Reduction of Diffusional Defocusing by Association of Analyte with High Molecular Weight Species. Appl. Spectrosc. 52:755 (1998).

Enderlein, J., D.L. Robbins, W.P. Ambrose, R.A. Keller. Molecular Shot Noise, Burst Size Distribution, and Single Molecule Detection in Fluid Flow: Effects of Multiple Occupancy. J. Phys. Chem. 102:6089 (1998).

Frank, G.J. Qui, M. Somsouk, Y. Weng, L. Somsouk, J.P. Nolan, and B. Shen. Partial Functional Deficiency of E160D Flap Endonuclease-1 Mutant In Vitro and In Vivo is Due to Defective Cleavage of DNA Substrates. Journal of Biological Chemistry 273:33064-33072 (1998).

Freyer J.P. Decreased Mitochondrial Function of Proliferating and Quiescent Cells Isolated from Multicellular Tumor Spheroids. J. Cell. Physiol. 176:138-149 (1998).


Gudi, S.R.P., J.P. Nolan, and J.A. Frangos. Modulation of GTPase Activity of G Proteins by Fluid Shear Stress and Phospholipid Composition. Proc. Natl. Acad. Sci. 95:2515-2519 (1998).

Hielscher, A.H., A.A. Eick, J.R. Mourant, D. Shen, J.P. Freyer, and I.J. Bigio. Diffuse Backscattering Mueller Matrix of Highly Scattering Media. Optics Exp. 1:441-453 (1998).

Jett, J.H., J.C. Martin, and R.C. Habbersett. Techniques for Flow Cytometer Alignment. In Current Protocols in Cytometry (CD-ROM). Eds John Wiley and Sons. Unit 1.10 (1998).

Keij, J.F. and J.A. Steinkamp. Flow Characterization and Classification of Multiple Dual-Color Fluorescent Microspheres Using Fluorescence Lifetime. Cytometry 33:318-323 (1998).

LaRue, K.E., E.M. Bradbury, and J.P. Freyer. Differential Regulation of Cyclin-Dependent Kinase Inhibitors in Monolayer and Spheroid Cultures of Tumoirigenic and Nontumorigenic Fibroblasts. Cancer Research 58:1305-1314 (1998).

Lynam, E., L.A. Sklar, C.W. Smith, B. Edwards, A. Taylor, and S.I. Simon. b2-Integrins Mediate Stable Adhesion in Collisions Between Neutrophils and ICAM-1 Expressing Cells. Journal of Leukocyte Biology. 64:622-630 (1998).

Machara, N.P., P.M. Goodwin, J. Enderlein, D.J. Semin, and R.A. Keller. Efficient Detection of Single Molecules Eluting off an Optically Trapped Microsphere. Bioimaging 6:33 (1998).

Nolan, J.P., H. Cai, K. Kommander, B. Lehnert, R. Nolan, M. Park, T. Ruscetti, B. Shen, L.A. Sklar. Real-Time Analysis of Molecular Assembly by Kinetic Flow Cytometry. In Advances in Optical Biophysics. (Eds. J.R. Lakowicz and J.B.A. Ross) Proceedings SPIE 3256:114 - 121 (1998)

Nolan, J.P., J.D. Chambers, and L.A. Sklar. Cytometric Approaches to the Study of Receptors. In Cytometric Cellular Analysis, Vol. 1. Phagocyte Function: A Guide for Research and Clinical Evaluation (Eds. J.P. Robinson and G. Babcock), John Wiley and Sons, pp 19 - 46 (1998).

Nolan, J.P., S. Lauer, E.R. Prossnitz, and L.A. Sklar. Flow Cytometry: A Versatile Tool for all Stages of Drug Discovery. Drug Discovery Today 4:173-180 (1998).

Nolan, J.P. and L.A. Sklar. The Emergence of Flow Cytometry for Sensitive, Real-Time Measurements of Molecular Interactions. Nature Biotechnology 16:633-638 (1998).

Ray, F.A., M.J. Waltman, J.M. Lehman, J.B. Little, J.A. Nickoloff, and P.M. Kraemer. Identification of SV40 T-Antigen Mutants that Alter T-Antigen-Induced Chromosome Damage in Human Fibroblasts. Cytometry 31:242-250 (1998).

Sailer, B.L., A.M. Barrasso, J.G. Valdez, J.M. Cobo, J.A. DÆAnna, and H.A. Crissman. Reduction in the Radiation-Induced Late S Phase and G2 Blocks in HL-60 Cell Populations by Amiloride, an Efficient Inhibitor of the Na+/H+ Transporter. Cancer Research 58:413-420 (1998).

Sailer, B.L., J.A. Steinkamp, and H.A. Crissman. Flow Cytometric Analysis of DNA-Binding Probes. Eur. J. Histochem. 42:19-28 (1998).


Sailer, B.L., J.G. Valdez, J.A. Steinkamp, and H.A. Crissman. Apoptosis Induced With Different Cycle Perturbing Agents Produces Differential Changes in the Fluorescence Lifetime of DNA-Bound Ethidium Bromide. Cytometry 31:208-216 (1998).

Song, X., J.P. Nolan, and B. Swanson. An Optical Biosensor Based on Fluorescence Self-Quenching and Energy Transfer: Ultrasensitive and Specific Detection of Protein Toxins. Journal of the American Chemical Society 120:11514-11515 (1998).

Song, X., J.P. Nolan, B Swanson. Optical Signal Transduction Triggered by Protein-Ligand Binding: Detection of Toxins Using Multivalent Receptors. Journal of the American Chemical Society 120:4873-4874 (1998).

Steinkamp, J.A. and J. F. Keij. Fluorescence Lifetime Measurement of Free and Cell/ Particle-Bound Fluorophore by Phase-Sensitive Flow Cytometry. Proceedings of Advances in Optical Biophysics. SPIE 3256:154-161 (1998).

Steinkamp, J.A., J.D. Parson, and J.F. Keij. Progress Towards Combined Phase and Amplitude Demodulation Fluorescence Lifetime Measurements by Flow Cytometry. Proceedings of Optical Investigations of Cells In Vitro and In Vivo, SPIE 3260:236-244 (1998).

Van Orden, A., P.M. Goodwin, and R.A. Keller. Single-Molecule Identification in Flowing Sample Streams by Fluorescence Burst Size and Intraburst Fluorescence Decay Rate. Anal. Chem. 70:1444 (1998).

Van Orden, A. and R. A. Keller. Fluorescence Correlation Spectroscopy for Rapid Multicomponent Analysis in a Capillary Electrophoresis System. Anal. Chem., 70:4463 (1998)

Vilven, J., M. Domalewski, E. Prossnitz, R. Ye, R. Harris, R. Freer, and L.A. Sklar. Strategies for Positioning Fluorescent Probes and Crosslinkers on Formyl Peptide Ligands. J. Signal Transduction and Receptor Research 18:187 (1998).

Xie, G., R.C. Habbersett, Y. Jia, S.R. Peterson, B.E. Lehnert, E.M. Bradbury, and J.A. DÆAnna. Requirements for p53 and the ATM Gene Product in the Regulation of G1/S and S Phase Checkpoints. Oncogene 16:721-736 (1998).



1997


Buranda, T., G. Jones, J.P. Nolan, R. Harris, G. Lopez, and L.A. Sklar. Molecular Recognition Mediated Detection of Analytes Via Resonance Energy-Transfer. ANYL 213:226 (1997).

Chen, F., A. Nastasi, Z. Shen, M. Brenneman, H.A. Crissman, and D.J. Chen. Cell-Cycle-Dependent Protein Expression of Mammalian Homologs of Yeast DNA Double Strand Break Repair Genes RAD51 and RAD52. Mutation Research-DNA Repair 384:205-211 (1997).

DÆAnna, J.A., J.G. Valdez, R.C. Habbersett, and H.A. Crissman. Association of G1/S-Phase and Late S-Phase Checkpoints with Regulation of Cyclin-Dependent Kinases in Chinese Hamster Ovary Cells. Radiation Research 148:260-271 (1997).

Gadbois, D.M., E.M. Bradbury, and B.E. Lehnert. Control of Radiation-Induced G1 Arrest by Cell-Substratum Interactions. Cancer Research 57:1151-1156 (1997).

Gadbois, D.M. and B.E. Lehnert. Temporal Position of G1 Arrest in Normal Human Fibroblasts after Exposure to _-Rays. Exp. Cell Research 232:161-166 (1997).

Goodwin, P.M., H. Cai, J.H. Jett, S.L. Ishaug-Riley, N.P. Machara, D.J. Semin, A. Van Orden, and RA. Keller. Application of Single Molecule Detection to DNA Sequencing. Nucleosides & Nucleotides 16:543-550 (1997).

Hall, A., B. Wilson, J. Oliver, and L.A. Sklar. Relationship of Ligand-Receptor Dynamics and Actin Polymerization in RBL Cells Transfected with the Formyl Peptide Receptor. J. Leuk. Biol. 62:535-542 (1997).

Kunz-Schughart, L.A. and J.P. Freyer. Adaptation of an Automated Selective Dissociation Procedure to Multicellular Spheroids of Oncogene-Transformed Fibroblasts. In Vitro Cell. Develop. Biol. 33:73-76 (1997).

Kunz-Schughart, L.A., R.C. Habbersett and J.P. Freyer. Mitochondrial Distribution and Activity in Oncogene-Transformed Rat Fibroblasts Isolated From Multicellular Spheroids. Am. J. Physiol. 273:C1487-C1595 (1997).

Larson, R., D. Brown, and L.A. Sklar. Retinoic Acid Induces Aggregation of the Acute Promyelocytic Leukemia Cell Line NB-4 by Utilization of LFA-1 and 1CAM-2. Blood 90:2747-2757 (1997)

Lee, R.J., D.E. Lujan, A.L. Hall, L.A. Sklar, B.S. Wilson, and J.M. Oliver. Cooperation between the Fc_R1 and Formyl Peptide Receptor Signaling Pathways in RBLFPR Cells: the Contribution of Receptor-Specific Ca2+ Mobilization Responses. BBRC 235:812-819 (1997).

Narayanan, P.K., J.M. Rudnick, E.A. Walthers, and H.A. Crissman. Modulation in Cell Cycle and Cyclin B1 Expression in Irradiated HeLa Cells and Normal Human Skin Fibroblasts Treated with Staurosporine and Caffeine. Exp. Cell Research 233:118-127 (1997).

Nolan, J.P. and R.H. Hammerstedt. Regulation of Membrane Stability and the Acrosome Reaction in Mammalian Sperm. FASEB Journal 11:670-682 (1997).

Robbins, D.L., J.P. Nolan, J.H. Jett, R.A. Keller, and L.A. Sklar. Analysis of Individual Lipoproteins and Liposomes. SPIE Proceedings: Ultrasensitive Biochemical Diagnosis II 2985:213-222 (1997).

Roslaniec, M.C., C.S. Bell-Prince, H.A. Crissman, J.J. Fawcett, P.M. Goodwin, R.C. Habbersett, J.H. Jett, R.A. Keller, J.C. Martin, B.L. Marrone, J.P. Nolan, M.S. Park, L.A. Sklar, J.A. Steinkamp, and L.S. Cram. New Flow Cytometry Technologies for the 21st Century. Human Cell 10:3-10 (1997).

Sailer, B.L., A.J. Nastasi, J.G. Valdez, J.A. Steinkamp, and H.A. Crissman. Differential Effects of Deuterium Oxide on the Fluorescence Lifetimes and Intensities of Dyes having Different Modes of Binding to DNA. J Histochem. Cytochem. 45:165-175 (1997).

Sailer, B.L., J.G. Valdez, J.A. Steinkamp and H.A. Crissman. Monitoring Uptake of Ellipticine and Its Fluorescence Lifetime in Relation to the Cell Cycle Phase by Flow Cytometry. Exp. Cell Research 236:259-267 (1997).

Seegers, J.C., M. de Kock, M.-L. Lottering, C.J.S. Grobler, D.H. van Papendorp, Y. Shou, R.C. Habbersett, and B.E. Lehnert. Effects of Gamma-Linolenic Acid and Arachidonic Acid on Cell Cycle Progression and Apoptosis Induction in Normal and Transformed Cells, Prostaglandins, Leukotrienes and Essential Fatty Acids 58(4):271-280 (1997).

Shen, B., J.P. Nolan, L.A. Sklar, and M.S. Park. Functional Analysis of Point Mutations in Human Flap Endonuclease-1 Active Site. Nucleic Acid Research 25:3332-3338 (1997).

Steinkamp, J.A., H.A. Crissman, B.E. Lehnert, N.M. Lehnert, and C. Deka. Frequency-Domain Flow Cytometry: Fluorescence Lifetime-Base Sensing Technology For Analyzing Cells and Chromosomes Labeled With Fluorescent Probes. In Proceedings of the International Society for Optical Engineering (SPIE), Advances in Fluorescence Sensing Technology III 2980:96-106 (1997).

Steinkamp, J.A., B.E. Lehnert and J.F. Keij. Phase-Sensitive Detection as a Means to Recover Fluorescence Signals From Interfering Backgrounds in Analytical Cytology Measurements. In Proceedings of Optical Diagnosis of Biological Fluids and Techniques in Analytical Cytology, The International Society for Optical Engineering (SPIE) 2982:447-455 (1997).

Zenin, V.V., N.D. Aksenov, A.N. Shatrova, N.V. Klopov, L.S. Cram, and A.I. Poletaev. Flow Analysis of Human Chromosome Sets by Means of a Mixing-Stirring Device. Advanced Techniques in Analytical Cytology, A.V. Priezzhev, T. Asakura, R.C. Leif, eds, SPIE 2982:395-402 (1997).

Zenin, V.V., N.D. Aksenov, A.N. Shatrova, N.V. Klopov, L.S. Cram, and A.I. Poletaev. Micro-mixing Device for Flow Cytometry Studies. Advanced Techniques in Analytical Cytology, A.V. Priezzhev, T. Asakura, R.C. Leif, eds, SPIE 2982:385-394 (1997).



1996


Ainsworth, T., E.B. Lynam, and L.A. Sklar. Neutrophil Function in Inflammation and Infection, in Cellular and Molecular Pathogenesis, Alphonse E. Sirica, Editor, Raven Press, NY, pp37-55 (1996).

Bennett, T., E.B. Lynam, L.A. Sklar, and S.A. Rogelj. Hydroxamate-based Metalloprotease Inhibitor Blocks Shedding of L-Selectin Adhesion Molecules from Leukocytes: Functional Consequences for Neutrophil Aggregation. J. Immunol. 156:3093 (1996).

Crissman, H.A. and A.J. Nastasi. Cell Cycle and Cell Proliferation Markers. in: Flow and Image Cytometry (A. Jacquemin-Sablon, ed. NATO ASI. Springer-Verlag Berlin-Heidelberg-New York-Tokyo, Part 2, pp 91-101 (1996).

Crissman, H.A., N. Oishi, and R.A. Tobey. Reversible Synchronization of Cultured Rodent and Human Diploid Fibroblasts in G2 Phase. Methods in Cell Science 18:179-186 (1996).

D'Anna, J.A., H.A. Crissman, J.G. Valdez, L.R. Gurley, and R.A. Tobey. Synchronization of Mammalian Cells in S Phase by Sequential Use of Isoleucine-Deprivation G1-or Serum-Withdrawal G0-Arrest and Aphidicolin Block. Methods in Cell Science 18:115-125 (1996).

Deka, C., B.E. Lehnert, N.M. Lehnert, G. Jones, L.A. Sklar, and J.A. Steinkamp. Analysis of Fluorescence Lifetime Quenching of FITC Antibodies by Phase Sensitive Flow Cytometry. Cytometry 25:271-279, 1996.

Deka, C., B.E. Lehnert, N.M. Lehnert, G.M. Jones, L.A. Sklar, and J.A. Steinkamp. Rapid Analysis of Fluorescence Quenching of FITC Conjugated Antibodies on Individual Cells by Phase-Sensitive Flow Cytometry. in Proceedings of the Optical Society of America, Biomedical Optics Symposium, Orlando, FL, pp. 44-46, March 18 - 22, 1996.

Deka, C. and J.A. Steinkamp. Time-Resolved Fluorescence Decay Measurements and Analysis on Single Cells by Flow Cytometry Using Electro-Optically Pulse-Modulated CW Laser Excitation. J. Applied Optics 33:4481-4489, 1996.

Domalewski, M.D., D.A. Guyer, N. Muthukumaraswamy, R.J. Freer, and L.A. Sklar. Fixation Traps Formyl Peptide Receptors in High and Low Affinity Forms that can be Regulated by GTP[S] in the Absence of Ligand. J. Rec. Res. 16:59 (1996).

Gadbois, D.M., H.A. Crissman, A.J. Nastasi, R.C. Habbersett, S-k. Wang, D.J. Chen, and B.E. Lehnert. Alterations in the Progression of Cells through the Cell Cycle after Exposure to Alpha Particles or Gamma Rays. Radiation Research 146:414-424 (1996).

Goodwin, P.M., R.L. Affleck, W.P. Ambrose, J.H. Jett, M.E. Johnson, J.C. Martin, J.T. Petty, J.A. Schecker, M. Wu, and R.A. Keller. Detection of Single Fluorescent Molecules in Flowing Sample Streams, in Computer Assisted Analytical Spectrometry, S.D. Brown, Editor; Wiley and Sons, 1996.

Goodwin, P.M., W.P. Ambrose, and R.A. Keller. Single Molecule Detection in Liquids by Laser-Induced Fluorescence. Acct. Chem. Res. 29, 607 (1996).

Guyer, D.A., K.L. Moore, E.B. Lyman, C.M. G. Schammel, S. Rogelj, R.P. McEver, and L.A. Sklar. PSGL-1 is a Ligand for L-Selectin in Neutrophil Aggregation, Bloos: Rapid Communication 88:2415 (1996).

Huang, Z., J.T. Petty, B.OÆQuinn, J.L. Longmire, N.C. Brown, J.H. Jett, and R.A. Keller. Large DNA Fragment Sizing by Flow Cytometry: Application to the Characterization of P1 Artificial Chromosomes (PAC) Clones. Nucleic Acids Research 24, 4202-4209 (1996).

Keller, R.A., W.P. Ambrose, P.M. Goodwin, J.H. Jett, J.C. Martin, and M. Wu. Single Molecule Fluorescence Analysis in Solution. Appl. Spec. 50:12A (1996).

Lynam, E., S. Rogelj, B. Edwards, and L.A. Sklar. Enhanced Aggregation of Human Neutrophils by MnCl2 or DTT Differentiates the Roles of L-Selectin and b2-Integrins. J. Leuk Biol. 60:271 (1996).

Nolan, J. P., B. Shen, M. Park, and L.A. Sklar. Kinetic Analysis of Flap Endonuclease by Flow Cytometry, Biochemistry 35:11668 (1996).

Remmers, A.E., R.G. Posner, and R.R. Neubig. Kinetics of Guanine Nucleotide Binding and Hydrolysis and G Protein Activation Measured by Fluorescent Guanine Nucleotide Analogs. J. Biol. Chem. 269:13771 (1996).

Sailer, B.L., A.J. Nastasi, J.G. Valdez, J.A. Steinkamp, and H.A. Crissman. Interactions of Intercalating Fluorochromes with DNA Analyzed by Conventional and Fluorescence Lifetime Flow Cytometry Utilizing Deuterium Oxide. Cytometry 25:164-172 (1996).

Shen, B., J.P. Nolan, L.A. Sklar, and M.S. Park. Essential Amino Acids for Substrate Binding and Catalysis of Human Flap Endonuclease-1. J. Biol. Chem. 271:9173-9176 (1996).

Wimmer, K.,D. Thoraval, J. Asakawa, R. Kuick, M. Kodaira, B. Lamb, J. Fawcett, T. Glover, L.S. Cram, and S. Hanash. Two-Dimensional Separation and Cloning of Chromosome 1 NotI-EcoRV-Derived Genomic Fragments. Genomics 38:124 (1996).

Wistrom, C.A., G.M. Jones, P.S. Tobias, and L.A. Sklar. Fluorescence Resonance Energy Transfer Analysis of Bacterial Lipopolysaccharide Conformation in Detergent Micelles. Biophys. J. 70:988-977 (1996)

Wright, P. S., D. Cross-Doersen, J.P.H. ThÆng, X.W. Guo, H.A. Crissman, E.M. Bradbury, L.R. Montgomery, F.Y. Thompson, D.E. Loudy, D.C. Beach, J.A. Dumont, J.O. Johnston, and A.J. Bitonti. A Ribonucleotide Reductase Inhibitor, MDL 101,731, Induces Apoiptosis and TRPM-2 mRNA Levels in Human Tumor Xenografts. Exp Cell Res 222:54-60 (1996).

 

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