Mietta Lillo
Contact Info
alillo@lanl.gov
505 606 0372
Profile
Mietta earned her PhD in Biochemistry at Brown University and after a 3 year post-doc at The Scripps Research institute she started working at LANL where she has been since May 2005. She is generating phage display substrate libraries for the investigation of substrate specificity of metalloproteases involved in the mechanism of action of some bio-warfare agents. She is also developing FRET-based systems for intracellular protease assays and producing recombinant proteolytic toxins.
Recent Publications
“Targeting heat shock proteins on cancer cells: selection, characterization and cell penetrating properties of a peptidic GRP78 ligand” Kim Y., Lillo A. M., Steiniger S.C.J., Liu Y., Ballatore C., Anichini A., Mortarini R., Zhou B, Felding-Habermann B., Janda K. D., Biochemistry 2006, 45, 9434-9444.
“Phage-dispalyed antibody libraries” Lillo A. M., McKenzie K. M. and Janda K. D., Cell Biology: A Laboratory Handbook 2006, Chp. 59, 491-496.
“A contiguous stretch of methionine residues mediates the energy-dependent internalization mechanism of a cell-penetrating peptide” Kim Y, Lillo A., Moss J. A., Janda K. D., Mol Pharm. 2005, 2, 528-535.
“A dimerization switch in the internalization mechanism of a cell-penetrating peptide” Moss J. A., Lillo A., Kim Y. S., Gao C., Ditzel H., Janda K. D., J Am Chem Soc. 2005, 127, 538-539.